Restoring Gut Health with Fecal Microbiota Transplant: Balancing Risks and Benefits

Name Professor Course code Date Microbiology (FMT). Fecal Microbiota Transplantation has gained prominence in recent years due to the increasing cases of  Clostridioides difficile infection (CDI). According to (Anonye) “Fecal microbiota transplantation (FMT) has been used as a treatment of last resort for recurrent C. difficile infections (CDI) with a cure rate of 85–90% after the first FMT.” Bacteriophages play a vital role in the function of the host microbiota. The procedure has been proved as ideal in the restoration of lost microbial function. Although FMT is regarded as highly effective, it carries risks. The question that arises is what constitutes a healthy gut phageome and how it influences human gut microbiota during the transfer from donor to recipient. How is it safe? Is the procedure stable? Donor microbiota can lead to serious and life-threatening conditions